2-氨基-4-甲基苯酚合成路线 （共 127 条）
反应条件
sulfuric acid Diazotization;
参考文献
Aschkinasi
Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), 1933 , vol. 6, p. 730,735
Chem. Zentralbl., 1935 , vol. 106, # I p. 2670
反应条件
1: With acetic acid 24 h; Reflux; 2: With sulfuric acid T=100°C; 2 h; 3: With potassium carbonate in water
参考文献
ARGENTA DISCOVERY LIMITED; ASTRAZENECA AB
Patent: WO2009/153536 A1, 2009 ;
Location in patent: Page/Page column 41-42 ;
WO 2009/153536 A1
参考文献
Wang, Renchao; Xu, Jiaxi
Arkivoc, 2010 , vol. 2010, # 9 p. 293 - 299
反应条件
TSA in neat (no solvent) T=80 - 90°C; 0.2 h; Reagent/catalyst;
参考文献
Farahi, Mahnaz; Karami, Bahador; Azari, Masume
Comptes Rendus Chimie, 2013 , vol. 16, # 11 p. 1029 - 1034
反应条件
1,3-dibromo-5,5-dimethyl-hydantoin T=20°C; 0.1 h;
参考文献
Hojati, Seyedeh Fatemeh; Maleki, Behrooz; Beykzadeh, Zahra
Monatshefte fur Chemie, 2011 , vol. 142, # 1 p. 87 - 91
参考文献
Drain; Daly; Davy; Horlington; Howes; Scruton; Selway
The Journal of pharmacy and pharmacology, 1970 , vol. 22, # 9 p. 684 - 693
反应条件
in pyridine T=95 - 120°C; 2 h;
参考文献
Agarwal, Nand L.; Schaefer, Wolfram
Journal of Organic Chemistry, 1980 , vol. 45, # 25 p. 5144 - 5149
反应条件
1: 37 percent / KOH / methanol / 3 h / Ambient temperature 2: 86 percent / 1) sodium hydrogensulfite; 2) pyridine / benzene; dioxane; H2O / 1) 20 min; 2) 3 h, reflux; View Scheme
参考文献
Ueno; Maeda; Koshitan
Journal of Heterocyclic Chemistry, 1982 , vol. 19, # 1 p. 189 - 191
参考文献
Bolognese, Adele; Parilli, Michelangelo
Heterocycles, 1992 , vol. 34, # 9 p. 1829 - 1833
参考文献
Butenandt,A. et al.
Justus Liebigs Annalen der Chemie, 1960 , vol. 632, p. 143 - 157
