1,2,4,5-四甲基苯合成路线 （共 381 条）
反应条件
nitrogen(IV) oxide in various solvent(s) T=20°C; 0.5 h; in the dark; Title compound not separated from byproducts;
参考文献
Acta Chemica Scandinavica, , vol. 50, # 11 p. 991 - 1008
反应条件
nitric acid in sulfuric acid T=25°C; 0.216667 h; in H2SO4 of different concentration, various time; Product distribution;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 1358 - 1366
参考文献
Willstaetter; Kubli
Chemische Berichte, 1909 , vol. 42, p. 4163
反应条件
1: With pyridine-2,6-dicarboxylic acid; FeCl3*6H2O; N-benzyl-N-(n-butyl)amine in 1,1-dimethylpropan-1-ol T=20°C; 0.166667 h; Sonication; 2: 1,2,4,5-tetramethyl benzene With dihydrogen peroxide in 1,1-dimethylpropan-1-ol T=20°C; 1.5 h; chemoselective reaction;
参考文献
Moeller, Konstanze; Wienhoefer, Gerrit; Schroeder, Kristin; Join, Benoit; Junge, Kathrin; Beller, Matthias
Chemistry - A European Journal, 2010 , vol. 16, # 34 p. 10300 - 10303
反应条件
HOF* CH3CN in chloroform; acetonitrile T=-15 - 0°C; 0.0166667 h;
参考文献
Kol, Moshe; Rozen, Shlomo
Journal of Organic Chemistry, 1993 , vol. 58, # 6 p. 1593 - 1595
反应条件
3-chloro-benzenecarboperoxoic acid in chloroform T=60 - 70°C; 0.5 h;
参考文献
Asakawa, Yoshinori; Matsuda, Reiko; Tori, Motoo; Sono, Masakazu
Journal of Organic Chemistry, 1988 , vol. 53, # 23 p. 5453 - 5457
反应条件
oxygen; zirconium (IV) sulphate; anhydrous cobalt diacetate; Manganese (II) acetate; 2,6-dihydroxypyromellitimide in acetic acid T=80 - 120°C; P=15001.5 Torr; 2 h; Product distribution / selectivity;
参考文献
US2011/71314 A1, ;
Page/Page column 13 ;
反应条件
oxygen; zirconium (IV) sulphate; anhydrous cobalt diacetate; Manganese (II) acetate; 2,6-dihydroxypyromellitimide in acetic acid T=60 - 70°C; P=6000.6 Torr; 2 h; Product distribution / selectivity;
参考文献
US2011/71314 A1, ;
Page/Page column 13-14 ;
反应条件
oxygen; zirconium (IV) sulphate; anhydrous cobalt diacetate; Manganese (II) acetate; 2,6-dihydroxypyromellitimide in acetic acid T=80 - 120°C; P=15001.5 Torr; 2 h; Product distribution / selectivity;
参考文献
US2011/71314 A1, ;
Page/Page column 13 ;
反应条件
water; oxygen; bromide; anhydrous cobalt diacetate; Manganese (II) acetate in acetic acid T=95°C; atmospheric pressure; Further byproducts.;
参考文献
Partenheimer, Walt
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 2-3 p. 297 - 306
