1,2,4,5-四甲基苯合成路线 （共 381 条）
反应条件
ozone in various solvent(s) T=-78°C; 8 h; Product distribution; Further Variations:Solvents;
参考文献
European Journal of Organic Chemistry, , # 10 p. 1899 - 1901
反应条件
phosphorus pentoxide T=330°C;
参考文献
Zhurnal Obshchei Khimii, , vol. 25, p. 1094,1095; engl. Ausg. S. 1051
反应条件
Nafion-H in toluene T=98 - 100°C; 12 h;
参考文献
Journal of Organic Chemistry, , vol. 48, # 19 p. 3360 - 3362
反应条件
1.1: toluene-4-sulfonic acid / dichloromethane / 96 h / 20 °C / |Inert atmosphere 2.1: sodium hydride / hexane; tetrahydrofuran / 1 h / -15 °C / |Inert atmosphere 2.2: 20 °C / |Inert atmosphere 3.1: sodium hydride / hexane; tetrahydrofuran / 1 h / -15 °C / |Inert atmosphere 3.2: 20 °C / |Inert atmosphere 4.1: potassium hydroxide / ethanol; water / 12 h / |Inert atmosphere; |Reflux 4.2: 2 h / pH 2 / |Inert atmosphere; |Reflux 5.1: diisobutylaluminium hydride / diethyl ether; toluene / 0.5 h / -78 °C / |Inert atmosphere 6.1: toluene-4-sulfonic acid / dichloromethane / 0 - 20 °C / |Inert atmosphere 6.2: 4 h / |Inert atmosphere; |Reflux View Scheme
参考文献
Arkivoc, , vol. 2010, # 4 p. 104 - 124
反应条件
1.1: sodium hydride / hexane; tetrahydrofuran / 1 h / -15 °C / |Inert atmosphere 1.2: 20 °C / |Inert atmosphere 2.1: sodium hydride / hexane; tetrahydrofuran / 1 h / -15 °C / |Inert atmosphere 2.2: 20 °C / |Inert atmosphere 3.1: potassium hydroxide / ethanol; water / 12 h / |Inert atmosphere; |Reflux 3.2: 2 h / pH 2 / |Inert atmosphere; |Reflux 4.1: diisobutylaluminium hydride / diethyl ether; toluene / 0.5 h / -78 °C / |Inert atmosphere 5.1: toluene-4-sulfonic acid / dichloromethane / 0 - 20 °C / |Inert atmosphere 5.2: 4 h / |Inert atmosphere; |Reflux View Scheme
参考文献
Arkivoc, , vol. 2010, # 4 p. 104 - 124
反应条件
1.1: sodium hydride / hexane; tetrahydrofuran / 1 h / -15 °C / |Inert atmosphere 1.2: 20 °C / |Inert atmosphere 2.1: potassium hydroxide / ethanol; water / 12 h / |Inert atmosphere; |Reflux 2.2: 2 h / pH 2 / |Inert atmosphere; |Reflux 3.1: diisobutylaluminium hydride / diethyl ether; toluene / 0.5 h / -78 °C / |Inert atmosphere 4.1: toluene-4-sulfonic acid / dichloromethane / 0 - 20 °C / |Inert atmosphere 4.2: 4 h / |Inert atmosphere; |Reflux View Scheme
参考文献
Arkivoc, , vol. 2010, # 4 p. 104 - 124
反应条件
1.1: potassium hydroxide / ethanol; water / 12 h / |Inert atmosphere; |Reflux 1.2: 2 h / pH 2 / |Inert atmosphere; |Reflux 2.1: diisobutylaluminium hydride / diethyl ether; toluene / 0.5 h / -78 °C / |Inert atmosphere 3.1: toluene-4-sulfonic acid / dichloromethane / 0 - 20 °C / |Inert atmosphere 3.2: 4 h / |Inert atmosphere; |Reflux View Scheme
参考文献
Arkivoc, , vol. 2010, # 4 p. 104 - 124
反应条件
1.1: diisobutylaluminium hydride / diethyl ether; toluene / 0.5 h / -78 °C / |Inert atmosphere 2.1: toluene-4-sulfonic acid / dichloromethane / 0 - 20 °C / |Inert atmosphere 2.2: 4 h / |Inert atmosphere; |Reflux View Scheme
参考文献
Arkivoc, , vol. 2010, # 4 p. 104 - 124
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone in acetic acid T=25°C; Rate constantMechanism;
参考文献
Journal of Organic Chemistry, , vol. 45, # 9 p. 1633 - 1637
反应条件
hydrogenchloride T=70°C; Einleiten von HCl und Behandlung des gebildeten Bis-chlormethyl-Derivats mit Zinkstaub und wss. NaOH;
参考文献
Chemische Berichte, , vol. 67, p. 1094,1096
