1: 129 mg / pyridine / 1) -20 deg C, 30 min; 2) 4 deg C, 2 h 2: 77 mg / NaI / acetone / 3 h / Heating 3: dimethylsulfoxide / 40 °C 4: aq. NaOH / methanol; H2O / 22 h View Scheme

sodium hydride; dimethyl sulfoxide in tetrahydrofuran 0.5 h;

1: 94.7 percent / acetonitrile 2: 33 percent / DMSO, NaH / tetrahydrofuran / 0.5 h View Scheme