1-N-boc-2-甲基-1,2-丙二胺合成路线 （共 4 条）
反应条件
triethylamine in dichloromethane
T=20°C; 24 h;
参考文献
ZALICUS PHARMACEUTICALS LTD.; PAJOUHESH, Hassan; GRIMWOOD, Mike; ZHU, Yongbao; DING, Yanbing
Patent: WO2011/26241 A1, 2011 ;
Location in patent: Page/Page column 37 ;
WO 2011/026241 A1
参考文献
Pittelkow, Michael; Lewinsky, Rasmus; Christensen, Jorn Bolstad
Synthesis, 2002 , # 15 p. 2195 - 2202
反应条件
sodium hydroxide in dichloromethane
T=0 - 20°C; 2 h;
参考文献
SANWA KAGAKU KENKYUSHO CO., LTD.
Patent: EP1595866 A1, 2005 ;
Location in patent: Page/Page column 11 ;
反应条件
in dichloromethane
1.) -40 deg C, 3 h, 2.) -40 deg C to r.t., overnight;
参考文献
Adamczyk, Maciej; Fishpaugh, Jeffrey R.; Heuser, Kevin J.
Organic Preparations and Procedures International, 1998 , vol. 30, # 3 p. 339 - 348
