2-甲氧基-5-[2-(3,4,5-三甲氧基苯基)乙基]苯酚合成路线 （共 27 条）
反应条件
hydrogen; palladium on activated charcoal in methanol; ethyl acetate Ambient temperature;
参考文献
Pettit, George R.; Singh, Sheo Bux; Boyd, Michael R.; Hamel, Ernest; Pettit, Robin K.; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 10 p. 1666 - 1672
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate
参考文献
Robinson, James E.; Taylor, Richard J. K.
Chemical Communications, 2007 , # 16 p. 1617 - 1619
反应条件
10 palladium on activated charcoal; hydrogen; ethylenediamine in methanol T=20°C; P=760.051 Torr; 1 h;
参考文献
Petrov, Ognyan I.; Gerova, Mariana S.; Chanev, Christo D.; Petrova, Katya V.
Synthesis, 2011 , # 22 art. no. Z71911SS, p. 3711 - 3715
反应条件
quinoline; hydrogen in hexane; toluene T=20°C; stereoselective reaction;
参考文献
Petrov, Ognyan I.; Gerova, Mariana S.; Chanev, Christo D.; Petrova, Katya V.
Synthesis, 2011 , # 22 art. no. Z71911SS, p. 3711 - 3715
反应条件
1: 69 percent / water; potassium hydroxide; carbon tetrachloride / 2-methyl-propan-2-ol / 12 °C / Heating 2: 99 percent / H2 / Pd/C / ethyl acetate View Scheme
参考文献
Chemical Communications, , # 16 p. 1617 - 1619
反应条件
1: Lawesson's reagent 2: potassium hydroxide / ethanol / 12 h / 0 - 20 °C 3: m-chloroperoxybenzoic acid; NaHCO3 / CH2Cl2 / 12 h / 20 °C 4: 69 percent / water; potassium hydroxide; carbon tetrachloride / 2-methyl-propan-2-ol / 12 °C / Heating 5: 99 percent / H2 / Pd/C / ethyl acetate View Scheme
参考文献
Chemical Communications, , # 16 p. 1617 - 1619
反应条件
1: potassium hydroxide / ethanol / 12 h / 0 - 20 °C 2: m-chloroperoxybenzoic acid; NaHCO3 / CH2Cl2 / 12 h / 20 °C 3: 69 percent / water; potassium hydroxide; carbon tetrachloride / 2-methyl-propan-2-ol / 12 °C / Heating 4: 99 percent / H2 / Pd/C / ethyl acetate View Scheme
参考文献
Chemical Communications, , # 16 p. 1617 - 1619
反应条件
1: 72 percent / tetrabutylammonium fluoride/silica / tetrahydrofuran / 12 h / 0 °C 2: 99 percent / H2 / Pd/C / ethyl acetate View Scheme
参考文献
Chemical Communications, , # 16 p. 1617 - 1619
反应条件
1: 1.) butyllithium / 1.) THF, RT, 20 min, 2.) THF, 10 min 2: 93 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.33 h 3: 94.4 percent / H2 / 10percent Pd/C / methanol; ethyl acetate / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 10 p. 1666 - 1672
反应条件
1: 1.) butyllithium / 1.) THF, RT, 20 min, 2.) THF, 10 min 2: 93 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.33 h 3: 94.4 percent / H2 / 10percent Pd/C / methanol; ethyl acetate / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 10 p. 1666 - 1672
