8-异丙氧基-1,4-二噁螺[4.5]癸烷合成路线 （共 4 条）
反应条件
silver(l) oxide
96 h;
参考文献
AC Immune, S.A.
Patent: US2011/280808 A1, 2011 ;
Location in patent: Page/Page column 74 ;
反应条件
silver(l) oxide
T=20°C; 288 h;
参考文献
GLAXO GROUP LIMITED
Patent: WO2007/107565 A1, 2007 ;
Location in patent: Page/Page column 60-61 ;
WO 2007/107565 A1
反应条件
1: sodium tetrahydroborate; methanol / 2 h / 20 °C
2: silver(l) oxide / 96 h
View Scheme
参考文献
AC Immune, S.A.
Patent: US2011/280808 A1, 2011 ;
反应条件
hydrogenchloride in tetrahydrofuran; water
T=20°C; 18 h;
参考文献
GLAXO GROUP LIMITED
Patent: WO2007/107566 A1, 2007 ;
Location in patent: Page/Page column 66 ;
WO 2007/107566 A1
