4-氨基-N-(2-甲氧基乙基)苯甲酰胺合成路线 （共 5 条）
反应条件
10 Pd/C; hydrogen in ethanol T=20°C;
参考文献
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE; SEBTI, Said M.; SCHOeNBRUNN, Ernst; LAWRENCE, Nicholas J.; LAWRENCE, Harshani R.; MARTIN, Matthew P.
Patent: WO2012/135641 A2, 2012 ;
Location in patent: Page/Page column 67 ;
反应条件
1: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / tetrahydrofuran / 1 h / 90 °C 2: ammonium formate / palladium on activated charcoal / ethanol / 2 h / 40 °C View Scheme
反应条件
1: BF3*OEt2 / 0.5 h 2: 52 percent / zinc dust, calcium chloride / ethanol; H2O / 5 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 1959 - 1962
反应条件
1: triethylamine / dichloromethane / 48 h / 20 °C / |Inert atmosphere 2: hydrogen; 10 Pd/C / ethanol / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 55, # 17 p. 7392 - 7416
反应条件
5 h; Ambient temperatureIrradiationfurther reagent: penta-1,3-diene, other time; Product distribution;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 1959 - 1962
