1: 90 percent / pyridine / Ambient temperature 2: 80.4 percent / Me3SiOTf / CH2Cl2 / 7 h / 0 - 5 °C 3: 93.1 percent / K2CO3 / methanol; H2O / Ambient temperature 4: 1.) n-BuLi, p-TsCl, HMPA; 2.) LiBr / 1.) n-hexane, ether, 0 deg C, 5 min; 2.) n-hexane, ether, RT, overnight 6: 63.2 percent / CaCO3, NCS / dimethylformamide; H2O / 0 - 25 °C 7: 50 percent / DBU / tetrahydrofuran / 4 h / Heating 8: 1.) EtMgBr / 1.) ether, RT, 30 min; 2.) 100 deg C, 10 min 9: 31.5 percent / AcOH / H2O / 0.5 h / Heating View Scheme