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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
2'-脱氧尿苷
合成路线
（共 165 条）
951-78-0
2'-脱氧尿苷
→
反应条件
反应条件
5'-amino-2',5'-dideoxyuridine phosphorylase; anhydrous phosphate Enzymatic reaction; Kinetics;
参考文献
Hatano, Akihiko; Harano, Aiko; Takigawa, Yoshikatsu; Naramoto, Yasuhiro; Toda, Keisuke; Nakagomi, Yuuichi; Yamada, Hideyuki
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 7 p. 3866 - 3870
951-78-0
2'-脱氧尿苷
→
反应条件
66-22-8
尿嘧啶
反应条件
18-crown-6 ether in dimethyl sulfoxide T=50°C; 36 h;
参考文献
Harayame, Takashi; Mori, Kenya; Yanada, Reiko; Ilo, Kumiko; Fujita, Yuki; Yoneda, Fumio
Journal of the Chemical Society, Chemical Communications, 1988 , # 17 p. 1171 - 1172
951-78-0
2'-脱氧尿苷
+
68-94-0
次黄嘌呤
→
反应条件
890-38-0
2'-脱氧肌苷
+
66-22-8
尿嘧啶
反应条件
potassium dihydrogenphosphate; multimeric uridine phosphorylase-Sepabeads-PEI-DX; purine nucleoside phosphorylase-glyoxyl-agarose in water T=45°C; pH=10; 5 h; Product distribution; Further Variations:pH-valuesTemperatures;
参考文献
Ubiali, Daniela; Rocchietti, Silvia; Scaramozzino, Francesca; Terreni, Marco; Albertini, Alessandra M.; Fernandez-Lafuente, Roberto; Guisan, Jose Manuel; Pregnolato, Massimo
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 11 p. 1361 - 1366
951-78-0
2'-脱氧尿苷
+
65-71-4
5-甲基脲嘧啶
→
反应条件
66-22-8
尿嘧啶
+
50-89-5
胸苷
反应条件
thymidine phosphorylase from Escherichia coli (E.C. 2.4.2.4) immobilized on Sepabeads EC-EP® in aq. phosphate buffer T=20°C; pH=7.5; 3 h; Enzymatic reaction; Catalytic behavior; Reagent/catalystTime;
参考文献
Serra, Immacolata; Bavaro, Teodora; Cecchini, Davide A.; Daly, Simona; Albertini, Alessandra M.; Terreni, Marco; Ubiali, Daniela
Journal of Molecular Catalysis B: Enzymatic, 2013 , vol. 95, p. 16 - 22
51-21-8
5-氟脲嘧啶
+
951-78-0
2'-脱氧尿苷
→
反应条件
66-22-8
尿嘧啶
+
50-91-9
5-氟-2'-脱氧脲核苷
反应条件
thymidine phosphorylase from Escherichia coli (E.C. 2.4.2.4) immobilized on Sepabeads EC-EP® in aq. phosphate buffer T=20°C; pH=7.5; 3 h; Enzymatic reaction; Catalytic behavior; Reagent/catalystpH-valueConcentration;
参考文献
Serra, Immacolata; Bavaro, Teodora; Cecchini, Davide A.; Daly, Simona; Albertini, Alessandra M.; Terreni, Marco; Ubiali, Daniela
Journal of Molecular Catalysis B: Enzymatic, 2013 , vol. 95, p. 16 - 22
951-78-0
2'-脱氧尿苷
→
反应条件
17039-17-7
+
66-22-8
尿嘧啶
反应条件
Trypanosoma crusi uridine phosphorylase; ortho-hydrogen phosphate in HEPES buffer T=25°C; pH=7.5; Enzymatic reaction; Kinetics;
参考文献
Vande Voorde, Johan; Gago, Federico; Vrancken, Kristof; Liekens, Sandra; Balzarini, Jan
Biochemical Journal, 2012 , vol. 445, # 1 p. 113 - 123
951-78-0
2'-脱氧尿苷
+
50-66-8
6-甲巯基嘌呤
→
反应条件
23526-11-6
反应条件
T=37°C; 7 h; alginate gel-entrapped cells of auxotrophic thymine-dependent strain of E. coli, ammonium acetate buffer pH 5.8;
参考文献
Votruba, Ivan; Holy, Antonin; Dvorakova, Hana; Guenter, Jaroslav; Hockova, Dana; et al.
Collection of Czechoslovak Chemical Communications, 1994 , vol. 59, # 10 p. 2303 - 2330
951-78-0
2'-脱氧尿苷
→
反应条件
23669-79-6
保护-2’-脱氧尿苷
反应条件
lithium carbonate; N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=20°C; Heating;
参考文献
Hansen, Anders S.; Thalhammer, Armin; El-Sagheer, Afaf H.; Brown, Tom; Schofield, Christopher J.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 4 p. 1181 - 1184
951-78-0
2'-脱氧尿苷
+
40615-36-9
4,4'-双甲氧基三苯甲基氯
→
反应条件
23669-79-6
保护-2’-脱氧尿苷
反应条件
pyridine 3 h; Ambient temperature;
参考文献
Avino, Anna; Garcia, Ramon Gueimil; Albericio, Fernando; Mann, Matthias; Wilm, Matthias; Neubauer, Gitte; Eritja, Ramon
Bioorganic and Medicinal Chemistry, 1996 , vol. 4, # 10 p. 1649 - 1658
951-78-0
2'-脱氧尿苷
+
443-72-1
6-甲基腺素
→
反应条件
2002-35-9
N6-甲基-2’-脱氧腺苷
反应条件
T=37°C; 16 h; alginate gel-entrapped cells of auxotrophic thymine-dependent strain of E. coli, ammonium acetate buffer pH 5.7;
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 59, # 10 p. 2303 - 2330
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