1-methyl-3-(4-nitrophenyl)benzene合成路线 （共 23 条）
反应条件
copper in N,N-dimethyl-formamide
6 h; Heating;
参考文献
Shudo, Koichi; Ohta, Toshiharu; Okamoto, Toshihiko
Journal of the American Chemical Society, 1981 , vol. 103, # 3 p. 645 - 653
反应条件
1.1: t-BuLi / pentane; diethyl ether / -78 °C
1.2: pentane; diethyl ether / -100 - 20 °C
2.1: Ba(OH)2*8H2O / Pd(PPh3)4 / 1,2-dimethoxy-ethane / Heating
View Scheme
参考文献
Klein, Markus; Erdinger, Lothar; Boche, Gernot
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2000 , vol. 467, # 1 p. 69 - 82
反应条件
water; palladium diacetate; sodium carbonate
T=80°C; Suzuki Coupling; 1 h; Green chemistry;
参考文献
Liu, Leifang; Dong, Yan; Tang, Nana
Green Chemistry, 2014 , vol. 16, # 4 p. 2185 - 2189
反应条件
barium dihydroxide; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether
Substitution; Suzuki reaction; Heating;
参考文献
Klein, Markus; Erdinger, Lothar; Boche, Gernot
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2000 , vol. 467, # 1 p. 69 - 82
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in N,N-dimethyl-formamide
T=90°C; Suzuki-Miyaura Coupling; 24 h; Schlenk technique;
参考文献
Yamamoto, Eiji; Izumi, Kiyotaka; Horita, Yuko; Ito, Hajime
Journal of the American Chemical Society, 2012 , vol. 134, # 49 p. 19997 - 20000
反应条件
tetrakis(triphenylphosphine) palladium(0) in toluene
T=110°C; Stille Cross Coupling; 12 h; Inert atmosphere;
参考文献
Qiu, Di; Meng, He; Jin, Liang; Wang, Shuai; Tang, Shengbo; Wang, Xi; Mo, Fanyang; Zhang, Yan; Wang, Jianbo
Angewandte Chemie - International Edition, 2013 , vol. 52, # 44 p. 11581 - 11584
Angew. Chem., 2013 , vol. 125, # 44 p. 11795 - 11798
反应条件
1: tert.-butylnitrite; toluene-4-sulfonic acid / 1,2-dichloro-ethane / 4 h / 0 °C / |Inert atmosphere
2: tetrakis(triphenylphosphine) palladium(0) / toluene / 12 h / 110 °C / |Inert atmosphere
View Scheme
参考文献
Qiu, Di; Meng, He; Jin, Liang; Wang, Shuai; Tang, Shengbo; Wang, Xi; Mo, Fanyang; Zhang, Yan; Wang, Jianbo
Angewandte Chemie - International Edition, 2013 , vol. 52, # 44 p. 11581 - 11584
Angew. Chem., 2013 , vol. 125, # 44 p. 11795 - 11798
反应条件
ammonium cerium(IV) nitrate in acetonitrile; benzene
24 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Arai, Noriyoshi; Narasaka, Koichi
Bulletin of the Chemical Society of Japan, 1995 , vol. 68, # 6 p. 1707 - 1714
反应条件
tert-Butyl thionitrate
2 h; Heating; Title compound not separated from byproducts;
参考文献
Oae, Shigeru; Shinhama, Koichi; Kim, Yong Hae
Bulletin of the Chemical Society of Japan, 1980 , vol. 53, # 7 p. 2023 - 2026
反应条件
in dichloromethane
T=120 - 130°C; P=0.001 Torr; 2 h; Product distributionMechanism;
参考文献
Bumagin, N. A.; Bumagina, I. G.; Beletskaya, I. P.
Journal of Organic Chemistry USSR (English Translation), 1984 , vol. 20, # 3 p. 411 - 417
Zhurnal Organicheskoi Khimii, 1984 , vol. 20, # 3 p. 457 - 464
