1: 63 percent / Grubbs second generation catalyst / CH2Cl2 / 0.25 h / 140 °C / microwave irradiation 2: TFA; water / acetonitrile / 0.33 h / 60 °C / microwave irradiation 3: 0.56 g / tetrahydrofuran / 20 h / Heating 4: 80 percent / lithium hydroxide / tetrahydrofuran; H2O / 0.33 h / 60 °C / microwave irradiation View Scheme

1: 63 percent / Grubbs second generation catalyst / CH2Cl2 / 0.25 h / 140 °C / microwave irradiation 2: TFA; water / acetonitrile / 0.33 h / 60 °C / microwave irradiation View Scheme

1: 63 percent / Grubbs second generation catalyst / CH2Cl2 / 0.25 h / 140 °C / microwave irradiation 2: TFA; water / acetonitrile / 0.33 h / 60 °C / microwave irradiation 3: 0.56 g / tetrahydrofuran / 20 h / Heating View Scheme