2-溴-N-叔丁基-4-硝基苯胺合成路线 (共 2 条)
反应条件
1: With bromine; acetic acid
T=15 - 30°C; 0.5 h;
2: With sodium hydrogencarbonate in water
pH=8 - 9;
参考文献
Vertex Pharmaceuticals Incorported
Patent: US2011/98311 A1, 2011 ;
反应条件
1: tert-butylamine / dimethyl sulfoxide
2: bromine / acetic acid
View Scheme
参考文献
Vertex Pharmaceuticals Incorported
Patent: US2011/98311 A1, 2011 ;