1-甲基-3-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)-1H-吡咯合成路线 （共 4 条）
反应条件
1: 1-methyl-pyrrole; chlorocatecholborane With AlCl3, aluminium chloride; triethylamine in dichloromethane T=20°C; Inert atmosphere; 2: 2,3-dimethylbutane-2,3-diol With triethylamine in dichloromethane T=20°C; 0.5 h; Irradiation;
参考文献
THE UNIVERSITY OF MANCHESTER; INGLESON, Michael James
Patent: WO2012/25760 A1, 2012 ;
Location in patent: Page/Page column 56-57 ;
反应条件
1: 1-methyl-pyrrole With AlCl3, aluminium chloride; chlorocatecholborane; triethylamine in dichloromethane T=20°C; 20 h; Inert atmosphere; 2: 2,3-dimethylbutane-2,3-diol in dichloromethane 1 h; Inert atmosphere; regioselective reaction;
参考文献
Angewandte Chemie - International Edition, , vol. 50, # 9 p. 2102 - 2106
反应条件
1: AlCl3, aluminium chloride; BCl3*C9H13N / dichloromethane / 3 h / 20 °C / |Schlenk technique; |Inert atmosphere 2: triethylamine / 1 h / 0 - 20 °C / |Inert atmosphere View Scheme
参考文献
Journal of the American Chemical Society, , vol. 135, # 1 p. 474 - 487
反应条件
triethylamine T=0 - 20°C; 1 h; Inert atmosphere;
参考文献
Bagutski, Viktor; Del Grosso, Alessandro; Carrillo, Josue Ayuso; Cade, Ian A.; Helm, Matthew D.; Lawson, James R.; Singleton, Paul J.; Solomon, Sophia A.; Marcelli, Tommaso; Ingleson, Michael J.
Journal of the American Chemical Society, 2013 , vol. 135, # 1 p. 474 - 487
