(R)-(+)-4-溴-3-羟基丁酸乙酯合成路线 (共 6 条)
反应条件
Daucus carota root in water T=20°C; 62 h; Title compound not separated from byproducts.;
参考文献
Journal of Organic Chemistry, , vol. 67, # 11 p. 3900 - 3903
反应条件
glucose dehydrogenase; D-glucose; BYueD; nicotinamide adenine dinucleotide phosphate in water T=30°C; pH=7; 12 h; aq. phosphate buffer; optical yield given as percent eeenantioselective reaction;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 15 p. 5463 - 5468
反应条件
1: methyl (3R)-3,4-dihydroxysuccinate With hydrogen bromide in acetic acid 2: ethanol in acetic acid Fischer esterification;
参考文献
Sinz, Christopher J; Rychnovsky, Scott D
Tetrahedron, 2002 , vol. 58, # 32 p. 6561 - 6576
反应条件
Candida antarctica lipase B in tert-butyl methyl ether T=60°C; 1 h; TemperatureTime;
参考文献
Advanced Synthesis and Catalysis, , vol. 355, # 9 p. 1808 - 1816
反应条件
ethanol; hydrogenchloride
参考文献
Gopalan; Sih
Tetrahedron Letters, 1984 , vol. 25, # 46 p. 5235 - 5238
反应条件
Candida antarctica lipase B in diethyl ether T=60°C; 0.5 h; Time;
参考文献
Advanced Synthesis and Catalysis, , vol. 355, # 9 p. 1808 - 1816