6-(三氟甲基)-1H-吲唑合成路线 （共 3 条）
反应条件
acetic anhydride; dinitrogen trioxide; acetic acid T=0°C; 14 h;
参考文献
EP2045253 A1, ;
Page/Page column 46 ;
EP 2045253 A1
反应条件
1.1: lithium tetramethylpiperidine / hexane; diethyl ether / 0.25 h / -78 °C 1.2: hexane; diethyl ether / 3 h / Heating 2.1: KOH / ethanol View Scheme
参考文献
Tetrahedron Letters, , vol. 45, # 8 p. 1769 - 1771
反应条件
iodine; potassium hydroxide in N,N-dimethyl-formamide T=20°C; 3 h;
参考文献
ASAHI KASEI PHARMA CORPORATION
Patent: US2010/29733 A1, 2010 ;
Location in patent: Page/Page column 39-40 ;
US 20100029733 A1
