1: With borane-THF in tetrahydrofuran T=70°C; 2 h; Inert atmosphere; 2: With hydrogenchloride; methanol in tetrahydrofuran; water 1 h; Inert atmosphereReflux; 3: With sodium hydroxide in water
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: US2011/21500 A1, 2011 ;
Location in patent: Page/Page column 47 ;
1: With borane-THF in tetrahydrofuran T=70°C; 2 h; Inert atmosphere; 2: With hydrogenchloride; methanol; water in tetrahydrofuran 1 h; Reflux; 3: With sodium hydroxide in water
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: US2011/195954 A1, 2011 ;
Location in patent: Page/Page column 104 ;
