1: 86 percent / 0.15 M aqueous LiOH / tetrahydrofuran / 4 h / Heating 2: 1.) pyridinium chlorochromate, sodium acetate, 2.) 0.15 M aqueous LiOH / 1.) CH2Cl2, 1 h, room temperature, 2.) THF, 5 min, room temperature View Scheme

&nbsp;Yield given. Multistep reaction;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 74 percent / calcium hydride, tetra-n-butylammonium iodide / toluene / Heating<br />2: 59 percent / azobis(isobutyronitrile), SO₂Cl₂ / CCl₄ / 2.5 h / -10 &deg;C / Irradiation<br />3: 1.) DBU, 2.) ozone / 1.) 150 min, 90 deg C, 2.) CH₂Cl₂/methanol, -78 deg C<br /> <br /> &nbsp;

<b>Multi-step reaction with 5 steps<br /> </b>1: pyridine<br />2: 1.) O₂, 2.) H₂ / 2.) PtO₂*H₂O / 1.) CH₂Cl₂/pyridine, irradiation, 14 h, 15 deg C, 2.) ethyl acetate, room temperature, atmospheric pressure, 10 h<br />3: 74 percent / calcium hydride, tetra-n-butylammonium iodide / toluene / Heating<br />4: 59 percent / azobis(isobutyronitrile), SO₂Cl₂ / CCl₄ / 2.5 h / -10 &deg;C / Irradiation<br />5: 1.) DBU, 2.) ozone / 1.) 150 min, 90 deg C, 2.) CH₂Cl₂/methanol, -78 deg C<br /> <br /> &nbsp;