2-(4-氯苯基硫代)烟酸合成路线 （共 3 条）
反应条件
potassium hydroxide in diethylene glycol
T=180°C; 6.5 h;
参考文献
Monge; Martinez-Merino; Cenarruzabeitia; et al.
European Journal of Medicinal Chemistry, 1985 , vol. 20, # 1 p. 61 - 66
反应条件
1: dimethylformamide / 0.5 h / Heating
2: 84 percent / potassium hydroxide / bis-(2-hydroxy-ethyl) ether / 6.5 h / 180 °C
View Scheme
参考文献
Monge; Martinez-Merino; Cenarruzabeitia; et al.
European Journal of Medicinal Chemistry, 1985 , vol. 20, # 1 p. 61 - 66
反应条件
thionyl chloride
1.5 h; Heating;
参考文献
Liegeois; Rogister; Bruhwyler; Damas; Thuy Phuong Nguyen; Inarejos; Chleide; Mercier; Delarge
Journal of Medicinal Chemistry, 1994 , vol. 37, # 4 p. 519 - 525
