4-氨基-N-(4-甲基苯基)苯甲酰胺合成路线 （共 6 条）
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate P=750.075 Torr;
参考文献
Kakuta, Hiroki; Zheng, Xiaoxia; Oda, Hiroyuki; Harada, Shun; Sugimoto, Yukio; Sasaki, Kenji; Tai, Akihiro
Journal of Medicinal Chemistry, 2008 , vol. 51, # 8 p. 2400 - 2411
反应条件
K3PO4*3H2O; N-methyl-2-(methylamino)ethylamine in toluene T=110°C; 18 h; Inert atmosphere;
参考文献
Yao, Zijian; Wei, Xianwen
Chinese Journal of Chemistry, 2010 , vol. 28, # 11 p. 2260 - 2268
反应条件
1: With ethylenediamine in ethanol Reflux; 2: With water
参考文献
Zhichkin, Paul E.; Peterson, Lisa H.; Beer, Catherine M.; Rennells, W. Martin
Journal of Organic Chemistry, 2008 , vol. 73, # 22 p. 8954 - 8959
反应条件
1: Et3N / CH2Cl2 / 0.08 h / Ambient temperature 2: Sn, 6 N HCl / tetrahydrofuran / 1 h / 50 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 29, # 3 p. 417 - 423
反应条件
1: Et3N / CH2Cl2 / 0.08 h / Ambient temperature 2: Sn, 6 N HCl / tetrahydrofuran / 1 h / 50 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 29, # 3 p. 417 - 423
反应条件
pyridine
T=60°C; 1.5 h; Yield given;
参考文献
Ogata, Masaru; Matsumoto, Hiroshi; Shimizu, Sumio; Kida, Shiro; Wada, Toru; et al.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 3 p. 417 - 423
