palladium on activated charcoal; hydrogen in 1,4-dioxane; water T=85°C; 16 h;

<b>Multi-step reaction with 3 steps<br /> </b>1: 84 percent / diethyl ether / Ambient temperature<br />2: 91 percent / lithium bis(trimethylsilyl)amide / tetrahydrofuran / 1 h / -78 &deg;C<br />3: 79 percent / 3 h / -78 deg C -&gt; RT<br /> <br /> &nbsp;

3&nbsp;h;&nbsp;&nbsp;-78 deg C -&gt; RT;&nbsp;<br /> &nbsp;