3-甲基-1H-吲唑-5-羧醛合成路线 (共 1 条)
反应条件
1: 5-Bromo-3-methyl-1H-indazole With tert.-butyl lithium in tetrahydrofuran; pentane
T=-78 - 70°C; 0.5 h; Inert atmosphere;
2: N,N-dimethyl-formamide in tetrahydrofuran; pentane
T=-78 - 20°C; 2 h; Inert atmosphere;
参考文献
BIGNAN, Gilles; Gaul, Micheal; Xu, Guozhang; Zhao, Bao-Ping
Patent: US2011/150864 A1, 2011 ;
Location in patent: Page/Page column 206 ;