1-(1-羟基-5,6,7,8-四氢萘-2-基)乙酮合成路线 （共 4 条）
反应条件
aluminium trichloride in 1,2-dichloro-benzene
T=80°C; Fries rearrangement; 12 h;
参考文献
Pallavicini, Marco; Budriesi, Roberta; Fumagalli, Laura; Ioan, Pierfranco; Chiarini, Alberto; Bolchi, Cristiano; Ugenti, Maria Paola; Colleoni, Simona; Gobbi, Marco; Valoti, Ermanno
Journal of Medicinal Chemistry, 2006 , vol. 49, # 24 p. 7140 - 7149
反应条件
1: 5,6,7,8-tetrahydro-naphthalen-1-ol With titanium tetrachloride
T=20°C;
2: acetyl chloride T=20 - 120°C; 1.25 h;
参考文献
Bensari, Ahlem; Zaveri, Nurulain T.
Synthesis, 2003 , # 2 p. 267 - 271
反应条件
1: 100 percent / pyridine / CH2Cl2 / 3 h
2: 100 percent / aluminum chloride / 1,2-dichloro-benzene / 12 h / 80 °C
View Scheme
参考文献
Pallavicini, Marco; Budriesi, Roberta; Fumagalli, Laura; Ioan, Pierfranco; Chiarini, Alberto; Bolchi, Cristiano; Ugenti, Maria Paola; Colleoni, Simona; Gobbi, Marco; Valoti, Ermanno
Journal of Medicinal Chemistry, 2006 , vol. 49, # 24 p. 7140 - 7149
参考文献
Lacey,R.N.
Journal of the Chemical Society, 1960 , p. 3153 - 3160
