2,3,4-三-O-乙酰基-beta-L-吡喃岩藻糖基叠氮化物合成路线 （共 7 条）
反应条件
sodium azide in acetonitrile
1.5 h; Heating1.) reflux, 90 min, 2.) RT, 17 h;
参考文献
Abbott, Shaun D.; Gagnon, Lyne; Lagraoui, Mouna; Kadhim, Salam; Attardo, Giorgio; Zacharie, Boulos; Penney, Christopher L.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 11 p. 1909 - 1926
反应条件
trimethylsilylazide; silver perchlorate; tin(IV) chloride in dichloromethane; toluene
T=20°C; 3 h;
参考文献
Badaea, Concepcion; Souard, Florence; Vicent, Cristina
Journal of Organic Chemistry, 2012 , vol. 77, # 23 p. 10870 - 10881
反应条件
sodium azide in N,N-dimethyl-formamide
1) 50 deg C, 2 h, 2) 70 deg C, 1 h;
参考文献
Sabesan; Neira
Carbohydrate Research, 1992 , vol. 223, p. 169 - 185
反应条件
trimethylsilylazide; tin(IV) chloride in dichloromethane
T=0 - 20°C; Inert atmosphere; optical yield given as percent de;
参考文献
Palomo, Claudio; Aizpurua, Jesus M.; Balentova, Eva; Azcune, Itxaso; Santos, J. Ignacio; Jimenez-Barbero, Jesus; Canada, Javier; Miranda, Jose Ignacio
Organic Letters, 2008 , vol. 10, # 11 p. 2227 - 2230
反应条件
1: 100 percent / aq. HBr, AcOH / 5 h / Ambient temperature
2: 67 percent / NaN3 / acetonitrile / 1.5 h / Heating; 1.) reflux, 90 min, 2.) RT, 17 h
View Scheme
参考文献
Abbott, Shaun D.; Gagnon, Lyne; Lagraoui, Mouna; Kadhim, Salam; Attardo, Giorgio; Zacharie, Boulos; Penney, Christopher L.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 11 p. 1909 - 1926
反应条件
1: 56 percent / DMAP / CH2Cl2 / 1) -10 to 0 deg C, 2 h, 2) 4 deg C, 1 h
2: 76 percent / NaN3 / dimethylformamide / 1) 50 deg C, 2 h, 2) 70 deg C, 1 h
View Scheme
参考文献
Sabesan; Neira
Carbohydrate Research, 1992 , vol. 223, p. 169 - 185
反应条件
1: ethyl acetate / |Reflux
2: trimethylsilylazide; tin(IV) chloride; silver perchlorate / toluene; dichloromethane / 3 h / 20 °C
View Scheme
参考文献
Badaea, Concepcion; Souard, Florence; Vicent, Cristina
Journal of Organic Chemistry, 2012 , vol. 77, # 23 p. 10870 - 10881
