α-乙基-2,6-二氟-3-吡啶甲醇合成路线 (共 2 条)
反应条件
1: 2,6-di-fluoro-pyridine With lithium diisopropyl amide in tetrahydrofuran
T=-78°C; 0.5 h;
2: propionaldehyde in tetrahydrofuran
T=-78°C; 0.5 h;
参考文献
Dunn, Robert F.; Kuester, Eric Mikal; Conticello, Richard D.; Hopper, Allen T.
Patent: US2007/254913 A1, 2007 ;
Location in patent: Page/Page column 61-62 ;
US 20070254913 A1
反应条件
pyridinium chlorochromate in chloroform
T=20°C; 16 h;
参考文献
Dunn, Robert F.; Kuester, Eric Mikal; Conticello, Richard D.; Hopper, Allen T.
Patent: US2007/254913 A1, 2007 ;
Location in patent: Page/Page column 62 ;
US 20070254913 A1