1.1: acetic acid / 1,2-dichloro-ethane / 0.25 h 1.2: 24 h / 20 °C 2.1: bis-triphenylphosphine-palladium(II) chloride; sodium carbonate / water; acetonitrile / 0.2 h / 140 °C / Microwave irradiation 3.1: hydrogenchloride / 1,4-dioxane; water / 3 h / 25 °C 4.1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 25 °C View Scheme