1.1: 89 percent / pyridine / 2.5 h / 0 °C 2.1: 96 percent / KBr; K3PO4 / (Ph3P)4Pd / dioxane / 26 h / 100 °C 3.1: 95 percent / 2,3-dichloro-5,6-dicyano-1,4-benzoquinone; p-TsOH*H2O / dioxane / 2.5 h / 50 °C 4.1: sodium dithionite / ethyl acetate; methanol; H2O / 4 h / 20 °C 5.1: n-BuLi / tetrahydrofuran; hexane / 0.33 h / -78 °C 5.2: 88.8 mg / tetrahydrofuran; hexane / 1.5 h / -78 - 0 °C 6.1: 90 percent / benzene / 36 h / 80 °C 7.1: 92 percent / methanolic HCl / CH2Cl2 / 30 h / 20 °C View Scheme

Stage #1: <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1209227', constants.ctx, '0')">n-butyllithium</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1730733', constants.ctx, '0')">hexane</a> <br />T=0&deg;C;&nbsp;1.5&nbsp;h;&nbsp;<br />Stage #2: &nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1730733', constants.ctx, '0')">hexane</a> <br />T=0&deg;C;&nbsp;0.833333&nbsp;h;&nbsp;<br />Stage #3: <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3587191', constants.ctx, '0')">dihydrogen peroxide</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '506007', constants.ctx, '0')">acetic acid</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1730733', constants.ctx, '0')">hexane</a> <br />T=0 - 20&deg;C;&nbsp;16&nbsp;h;&nbsp;&nbsp;Further stages.;&nbsp;<br /> &nbsp;