反应条件
1: 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0) / N,N-dimethyl-formamide / 0.5 h / 170 °C / Reflux; Inert atmosphere
2: trifluoroacetic acid / dichloromethane / 3 h / 20 °C
View Scheme
参考文献
ARAGON PHARMACEUTICALS, INC.; SMITH, Nicholas, D.; BONNEFOUS, Celine; JULIEN, Jackaline, D.
Patent: WO2011/103202 A2, 2011 ;
WO 2011/103202 A2
