1: (2S)-2-(leucylamino)-1-(trans-cinnamoylamino)-3-methylbutane hydrochloride; Z-Arg-OH hydrochloride With benzotriazol-1-ol; triethylamine in N,N-dimethyl-formamide pH=7.5; 2: dicyclohexyl-carbodiimide in N,N-dimethyl-formamide T=0 - 20°C; 3: With acetic acid; trifluoroacetic acid more than 3 stages;