3-甲氧基羰基-5-硝基苯硼酸频那醇酯合成路线 （共 4 条）
反应条件
potassium acetate; PdCl2(dpf)2 in dimethyl sulfoxide
T=80°C; 2 h;
参考文献
Roche Palo Alto LLC
Patent: US2009/163502 A1, 2009 ;
Location in patent: Page/Page column 37 ;
反应条件
potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in dimethyl sulfoxide
T=80°C; 4 h; Inert atmosphere;
参考文献
Broka, Chris Allen; Hawley, Ronald Charles
Patent: US2010/324056 A1, 2010 ;
Location in patent: Page/Page column 33 ;
US 20100324056 A1
反应条件
1: sulfur trioxide; iodine; sulfuric acid / sulfuric acid / 14 h / 20 - 85 °C
2: thionyl chloride / methanol / 2 h / 0 - 20 °C / Reflux
3: potassium acetate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / dimethyl sulfoxide / 4 h / 80 °C / Inert atmosphere
View Scheme
参考文献
Chen, Li; Dillon, Michael Patrick; Feng, Lichun; Hawley, Ronald Charles; Yang, Minmin
Patent: US2012/22067 A1, 2012 ;
US 20120022067 A1
反应条件
1: thionyl chloride / methanol / 2 h / 0 - 20 °C / Reflux
2: potassium acetate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / dimethyl sulfoxide / 4 h / 80 °C / Inert atmosphere
View Scheme
参考文献
Chen, Li; Dillon, Michael Patrick; Feng, Lichun; Hawley, Ronald Charles; Yang, Minmin
Patent: US2012/22067 A1, 2012 ;
US 20120022067 A1
