(R)-(+)-3-Boc-2,2-二甲基噁唑啉-4-甲醛合成路线 （共 41 条）
反应条件
1: 95 percent / H2 / Pd/C / ethyl acetate / 24 h / Ambient temperature 2: 93 percent / Dess-Martin periodinane / CH2Cl2 / 2 h / Ambient temperature View Scheme
参考文献
Synthesis, , # 10 p. 1146 - 1150
反应条件
1: BF3*Et2O / acetone / 1.5 h / Ambient temperature 2: 100 percent / LiAlH4 / tetrahydrofuran / 0.5 h / 0 °C View Scheme
参考文献
Synthesis, , # 12 p. 1707 - 1709
反应条件
1: 95 percent / BF3*Et2O / acetone / Ambient temperature 2: 93 percent / NaIO4, NaHCO3 / methanol; H2O / 0 °C 3: 69 percent / various solvent(s) / 6 h / 175 - 180 °C 4: OsO4, NMO / acetone / Ambient temperature 5: NaIO4, SiO2 / CH2Cl2 / Ambient temperature View Scheme
参考文献
Tetrahedron Letters, , vol. 38, # 38 p. 6779 - 6780
反应条件
1: OsO4, NMO / acetone / Ambient temperature 2: NaIO4, SiO2 / CH2Cl2 / Ambient temperature View Scheme
参考文献
Tetrahedron Letters, , vol. 38, # 38 p. 6779 - 6780
反应条件
1: LiBH4 / tetrahydrofuran / 12 h / Ambient temperature 2: 94 percent / BF3*Et2O / acetone / 2 h / Ambient temperature 3: 98 percent / Bu4NF / tetrahydrofuran / 2 h / Ambient temperature 4: 93 percent / Dess-Martin periodinane / CH2Cl2 / 2 h / Ambient temperature View Scheme
参考文献
Synthesis, , # 10 p. 1146 - 1150
反应条件
1: 94 percent / BF3*Et2O / acetone / 2 h / Ambient temperature 2: 98 percent / Bu4NF / tetrahydrofuran / 2 h / Ambient temperature 3: 93 percent / Dess-Martin periodinane / CH2Cl2 / 2 h / Ambient temperature View Scheme
参考文献
Synthesis, , # 10 p. 1146 - 1150
反应条件
1: 98 percent / Bu4NF / tetrahydrofuran / 2 h / Ambient temperature 2: 93 percent / Dess-Martin periodinane / CH2Cl2 / 2 h / Ambient temperature View Scheme
参考文献
Synthesis, , # 10 p. 1146 - 1150
反应条件
1: 93 percent / NaIO4, NaHCO3 / methanol; H2O / 0 °C 2: 69 percent / various solvent(s) / 6 h / 175 - 180 °C 3: OsO4, NMO / acetone / Ambient temperature 4: NaIO4, SiO2 / CH2Cl2 / Ambient temperature View Scheme
参考文献
Tetrahedron Letters, , vol. 38, # 38 p. 6779 - 6780
反应条件
1: 69 percent / various solvent(s) / 6 h / 175 - 180 °C 2: OsO4, NMO / acetone / Ambient temperature 3: NaIO4, SiO2 / CH2Cl2 / Ambient temperature View Scheme
参考文献
Tetrahedron Letters, , vol. 38, # 38 p. 6779 - 6780
反应条件
1: Et3N / dioxane; H2O 2: methanol 3: CSA / acetone 4: LiAlH4 / diethyl ether / 0 °C 5: -78 °C / Swern ox. View Scheme
参考文献
Tetrahedron Letters, , vol. 30, # 29 p. 3799 - 3802
