(R)-(+)-3-Boc-2,2-二甲基噁唑啉-4-甲醛合成路线 （共 41 条）
反应条件
Yield given. Multistep reaction;
参考文献
Journal of the American Chemical Society, , vol. 119, # 33 p. 7865 - 7866
反应条件
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 1.5 h / 0 °C / Inert atmosphere 2.1: toluene-4-sulfonic acid / toluene / 1.5 h / Reflux; Inert atmosphere 3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 0 - 20 °C 4.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.58 h / -78 °C 4.2: 0.08 h / -78 - 0 °C View Scheme
参考文献
Synthesis, , vol. 2012, # 2 p. 304 - 310
反应条件
1.1: toluene-4-sulfonic acid / toluene / 1.5 h / Reflux; Inert atmosphere 2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 0 - 20 °C 3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.58 h / -78 °C 3.2: 0.08 h / -78 - 0 °C View Scheme
参考文献
Synthesis, , vol. 2012, # 2 p. 304 - 310
反应条件
1.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 0 - 20 °C 2.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.58 h / -78 °C 2.2: 0.08 h / -78 - 0 °C View Scheme
参考文献
Synthesis, , vol. 2012, # 2 p. 304 - 310
参考文献
Osada, Satoshi; Ishimaru, Takako; Kawasaki, Hiroshi; Kodama, Hiroaki
Heterocycles, 2006 , vol. 67, # 1 p. 421 - 431
反应条件
boron trifluoride diethyl etherate T=-80°C;
参考文献
Casiraghi, Giovanni; Colombo, Lino; Rassu, Gloria; Spanu, Pietro
Journal of the Chemical Society, Chemical Communications, 1991 , # 8 p. 603 - 604
反应条件
boron trifluoride diethyl etherate in dichloromethane T=-80°C; 6 h; Yield given. Yields of byproduct given;
参考文献
Casiraghi, Giovanni; Colombo, Lino; Rassu, Gloria; Spanu, Pietro; Fava, Giovanna Gasparri; Belicchi, Maria Ferrari
Tetrahedron, 1990 , vol. 46, # 16 p. 5807 - 5824
反应条件
Zr(OiPr)4·HOiPr; 1,1'-binaphthyl-2,2'-diol in toluene T=20°C; 4 h;
参考文献
Lorca, Miguel; Kuhn, Dan; Kurosu, Michio
Tetrahedron Letters, 2001 , vol. 42, # 36 p. 6243 - 6246
反应条件
1: Methyltriphenylphosphonium bromide With potassium hexamethylsilazane in tetrahydrofuran; toluene T=20°C; 1 h; 2: 1,1-Dimethylethyl (R)-4-formyl-2,2-dimethyl-3-oxazolidinecarboxylate in tetrahydrofuran; toluene T=20°C; 3.5 h;
参考文献
Keyes, Robert F.; Carter, Justin J.; Zhang, Xiaolin; Ma, Zhenkun
Organic Letters, 2005 , vol. 7, # 5 p. 847 - 849
反应条件
sodium hexamethyldisilazane in tetrahydrofuran Wittig reaction;
参考文献
Takahata, Hiroki; Banba, Yasunori; Ouchi, Hidekazu; Nemoto, Hideo; Kato, Atsushi; Adachi, Isao
Journal of Organic Chemistry, 2003 , vol. 68, # 9 p. 3603 - 3607
