4-溴-3-(三氟甲基)苄醇合成路线 （共 2 条）
反应条件
borane-THF in tetrahydrofuran
T=0 - 20°C;
参考文献
IRM LLC; CHENG, Dai; ZHANG, Guobao; HAN, Dong; GAO, Wenqi; PAN, Shifeng
Patent: WO2010/101849 A1, 2010 ;
Location in patent: Page/Page column 47-48 ;
WO 2010/101849 A1
反应条件
1: With lithium borohydride in tetrahydrofuran
10 h; Heating / reflux;
2: With hydrogenchloride; water in tetrahydrofuran
T=20°C;
参考文献
Daiichi Sankyo Company, Limited
Patent: EP2017263 A1, 2009 ;
Location in patent: Page/Page column 249-250 ;
EP 2017263 A1
