2-(3,4-二甲氧基苯基)-5-{[2-(3,4-二甲氧基苯基)乙基](甲基)氨基}戊腈合成路线 （共 2 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=80°C; 12 h;
参考文献
Singh, Kawaljit; Kumar, Malkeet; Pavadai, Elumalai; Naran, Krupa; Warner, Digby F.; Ruminski, Peter G.; Chibale, Kelly
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 14 p. 2985 - 2990
反应条件
1.1: diisopropylamine; n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C
1.2: 0.33 h / -78 °C
1.3: 1 h / 22 °C
2.1: potassium carbonate / N,N-dimethyl-formamide / 12 h / 80 °C
View Scheme
参考文献
Singh, Kawaljit; Kumar, Malkeet; Pavadai, Elumalai; Naran, Krupa; Warner, Digby F.; Ruminski, Peter G.; Chibale, Kelly
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 14 p. 2985 - 2990
