4-氯-2-三氟甲基喹啉-6-甲酸甲酯合成路线 (共 2 条)
反应条件
1: With trichlorophosphate T=110°C; 20 h; 2: With ammonium hydroxide in water Cooling with ice; 3: With hydrogenchloride in water pH=5;
参考文献
US2012/88746 A1, ;
Page/Page column 74 ;
反应条件
1.1: polyphosphoric acid / 125 °C 2.1: trichlorophosphate / 20 h / 110 °C 2.2: Cooling with ice 2.3: pH 5 View Scheme