hydrogenchloride; water in acetone T=50°C; 2.5 h;

1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / Cooling with ice 2: copper(l) iodide / N,N-dimethyl-formamide; toluene / 1 h / 140 - 150 °C 3: hydrogenchloride / acetone / 2.5 h / 50 °C View Scheme

1: copper(l) iodide / N,N-dimethyl-formamide; toluene / 1 h / 140 - 150 °C 2: hydrogenchloride / acetone / 2.5 h / 50 °C View Scheme

pyridine in acetonitrile 0.5 h; Ambient temperature;