1,4-二(4-溴苯基)-1,3-丁二炔合成路线 （共 10 条）
反应条件
copper(l) iodide; NiII chloride hexahydrate; N,N,N',N,-tetramethylethylenediamine; oxygen in tetrahydrofuran
T=20°C;
参考文献
Yin, Weiyan; He, Chuan; Chen, Mao; Zhang, Heng; Lei, Aiwen
Organic Letters, 2009 , vol. 11, # 3 p. 709 - 712
反应条件
copper(l) iodide; iodine; potassium carbonate in dimethyl sulfoxide
T=50°C; 24 h; Inert atmosphere;
参考文献
Liu, De-Xian; Li, Fei-Long; Li, Hong-Xi; Gao, Jun; Lang, Jian-Ping
Tetrahedron, 2014 , vol. 70, # 14 p. 2416 - 2421
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide in tetrahydrofuran; dichloromethane; acetonitrile
T=25°C; Sonogashira coupling; 24 h; Inert atmosphere; chemoselective reaction;
参考文献
Man, Wing Y.; Bock, Soeren; Zaitseva, Natasha N.; Bruce, Michael I.; Low, Paul J.
Journal of Organometallic Chemistry, 2011 , vol. 696, # 10 p. 2172 - 2176
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine in tetrahydrofuran
Sonogashira Cross-Coupling; 3 h;
参考文献
Christensen, Mikkel Andreas; Rimmen, Morten; Nielsen, Mogens Brondsted
Synlett, 2013 , vol. 24, # 20 art. no. ST-2013-D0815-L, p. 2715 - 2719
反应条件
copper(l) iodide; caesium carbonate; bis-triphenylphosphine-palladium(II) chloride in acetonitrile
T=85°C; Sonogashira cross-coupling; 1.5 h;
参考文献
Abreu, Ana S.; Ferreira, Paula M. T.; Queiroz, Maria-Joao R. P.; Gatto, Emanuela; Venanzi, Mariano
European Journal of Organic Chemistry, 2004 , # 19 p. 3985 - 3991
反应条件
copper diacetate in 1,4-dioxane
T=100°C; 3 h;
参考文献
Kumar, Vipan; Chipeleme, Alex; Chibale, Kelly
European Journal of Organic Chemistry, 2008 , # 1 p. 43 - 46
反应条件
pyridine; copper diacetate in methanol
T=40 - 45°C; 24 h;
参考文献
Hayashi, Naoto; Nishihara, Takashi; Matsukihira, Takuya; Nakashima, Hiroki; Miyabayashi, Keiko; Miyake, Mikio; Higuchi, Hiroyuki
Bulletin of the Chemical Society of Japan, 2007 , vol. 80, # 2 p. 371 - 386
反应条件
copper(l) iodide; 1,8-diazabicyclo[5.4.0]undec-7-ene in dimethyl sulfoxide
T=25°C;
参考文献
Jin, Hui; Kuang, Chunxiang
Chinese Journal of Chemistry, 2011 , vol. 29, # 3 p. 592 - 594
参考文献
Salkind; Fundyler
Zhurnal Obshchei Khimii, 1939 , vol. 9, p. 1725,1726
Chem. Zentralbl., 1940 , vol. 111, # I p. 1828
反应条件
in N,N-dimethyl-formamide
T=150°C; 1 h; Schlenk techniqueInert atmosphere;
参考文献
Tang, Jialiang; Ming, Ling; Zhao, Xiaoming
Synthesis (Germany), 2013 , vol. 45, # 12 art. no. SS-2013-H0207-OP, p. 1713 - 1718
