5-溴喹唑啉-2,4-二酮合成路线 （共 2 条）
反应条件
acetic acid in water
T=35°C;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; JOHNSON, James A.; LLOYD, John; FINLAY, Heather; JIANG, Ji; NEELS, James; DHONDI, Naveen Kumar; GUNAGA, Prashantha; BANERJEE, Abhisek; ADISECHAN, Ashokkumar
Patent: WO2011/28741 A1, 2011 ;
Location in patent: Page/Page column 203 ;
WO 2011/028741 A1
反应条件
1.1: sodium hydroxide; dihydrogen peroxide / 1.25 h / 80 °C
1.2: pH 4 - 5
2.1: acetic acid / water / 35 °C
View Scheme
参考文献
BRISTOL-MYERS SQUIBB COMPANY; JOHNSON, James A.; LLOYD, John; FINLAY, Heather; JIANG, Ji; NEELS, James; DHONDI, Naveen Kumar; GUNAGA, Prashantha; BANERJEE, Abhisek; ADISECHAN, Ashokkumar
Patent: WO2011/28741 A1, 2011 ;
WO 2011/028741 A1
