N-ethyl-N,N-diisopropylamine; trichlorophosphate T=20°C; 36 h; Reflux;

1.1: hydroxylamine hydrochloride; sodium sulfate; 1-[4-(4-methyl-piperazine-1-carbonyl)-phenyl]-3-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-urea / 2 h / 90 °C 2.1: sulfuric acid / 3 h / 90 °C 3.1: sodium hydroxide; dihydrogen peroxide / water / 2 h / 0 °C 3.2: 0 °C / pH 6 4.1: 3 h / 195 °C 5.1: N-ethyl-N,N-diisopropylamine; trichlorophosphate / 12 h / 130 °C View Scheme

1.1: sodium hydroxide; dihydrogen peroxide / water / 2 h / 0 °C 1.2: 0 °C / pH 6 2.1: 3 h / 195 °C 3.1: N-ethyl-N,N-diisopropylamine; trichlorophosphate / 12 h / 130 °C View Scheme

1.1: sulfuric acid / 3 h / 90 °C 2.1: sodium hydroxide; dihydrogen peroxide / water / 2 h / 0 °C 2.2: 0 °C / pH 6 3.1: 3 h / 195 °C 4.1: N-ethyl-N,N-diisopropylamine; trichlorophosphate / 12 h / 130 °C View Scheme

1: 3 h / 195 °C 2: N-ethyl-N,N-diisopropylamine; trichlorophosphate / 12 h / 130 °C View Scheme

1: acetic acid / 22 h / 20 °C 2: trichlorophosphate; N-ethyl-N,N-diisopropylamine / 36 h / 20 °C / |Reflux View Scheme