2-氯-5-氟-6-甲氧基烟酸甲酯合成路线 （共 2 条）
反应条件
1: 2-chloro-5-fluoro-6-oxo-1,6-dihydropyridine-3-carboxylic acid With lithium hydride in N,N-dimethyl-formamide T=0°C; 0.75 h; 2: methyl iodide in N,N-dimethyl-formamide T=20°C; 2 h;
参考文献
ARRAY BIOPHARMA INC.; ASTRAZENECA AB
Patent: WO2007/44084 A2, 2007 ;
Location in patent: Page/Page column 134 ;
WO 2007/044084 A2
反应条件
methanol T=20°C; 0.666667 h;
参考文献
EP2022793 A1, ;
Page/Page column 72 ;
EP2022793 A1, ;
Page/Page column 72 ;
EP 2022793 A1
