dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; potassium carbonate; cesium fluoride in 2-methyl tetrahydrofuran; water T=75°C; Suzuki-Miyaura Coupling; 16 h; Inert atmosphere;

1.1: potassium carbonate / methanol / 4 h / 66 °C / Inert atmosphere 2.1: lithium hexamethyldisilazane / N,N-dimethyl-formamide / -15 - -10 °C / Inert atmosphere 2.2: -78 - -65 °C / Inert atmosphere 3.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride View Scheme

1.1: lithium hexamethyldisilazane / N,N-dimethyl-formamide / -15 - -10 °C / Inert atmosphere 1.2: -78 - -65 °C / Inert atmosphere 2.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride View Scheme