4-羟基-N-甲基-3-硝基苯磺酰胺合成路线 （共 5 条）
反应条件
ammonium formate; palladium on activated charcoal in ethanol T=20 - 80°C;
参考文献
GLAXOSMITHKLINE LLC; KALLANDER, Lara, S.; LAWHORN, Brian, Griffin; PHILIP, Joanne; ZHAO, Yongdong
Patent: WO2011/88027 A1, 2011 ;
Location in patent: Page/Page column 60-61 ;
反应条件
4-(N,N-dimethlyamino)pyridine in tetrahydrofuran
T=20°C;
参考文献
GLAXOSMITHKLINE LLC; KALLANDER, Lara, S.; LAWHORN, Brian, Griffin; PHILIP, Joanne; ZHAO, Yongdong
Patent: WO2011/88027 A1, 2011 ;
Location in patent: Page/Page column 60 ;
参考文献
Lavrishchev,V.A. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1960 , vol. 30, # 9 p. 3064 - 3072,3037 - 3044
反应条件
1: urea / 200 °C
2: aq. NaOH
View Scheme
参考文献
Lavrishchev,V.A. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1960 , vol. 30, # 9 p. 3064 - 3072,3037 - 3044
反应条件
1: NaOH
2: urea / 200 °C
3: aq. NaOH
View Scheme
参考文献
Lavrishchev,V.A. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1960 , vol. 30, # 9 p. 3064 - 3072,3037 - 3044
