4-甲氧基-2-硝基苯胺合成路线 （共 138 条）
反应条件
TiO2-P25 nanoparticles in acetonitrile 3 h; UV-irradiation;
参考文献
Annadhasan; Selvam; Swaminathan
Synthetic Communications, 2012 , vol. 42, # 10 p. 1500 - 1508
反应条件
1: 17 percent / As2O5, H3PO4 / 1 h / 100 °C 2: 100 percent / H2 / Raney-Ni / 1 h / 20 °C / 2585.74 Torr View Scheme
参考文献
McChesney; Sarangan; Hufford
Journal of Pharmaceutical Sciences, 1984 , vol. 73, # 12 p. 1854 - 1856
反应条件
1: 50 percent / 50percent NaH in oil / tetrahydrofuran; dioxane / Heating 2: 3.5 g / hydrogen / 10percent Pd/C / methanol / 2280 Torr View Scheme
参考文献
Heterocycles, , vol. 48, # 7 p. 1347 - 1363
反应条件
1: (i) aq. NaNO2, H2SO4, (ii) /BRN= 1209228/, aq. NH2OH, aq. H2SO4, NaOAc, CuSO4, Na2SO3 2: aq. NaOH View Scheme
参考文献
Gal'bershtam,M.A.; Budarina,Z.N.
Zhurnal Organicheskoi Khimii, 1969 , vol. 5, # 5 p. 953 - 956,938 - 941
反应条件
sodium hydride in tetrahydrofuran 12 h; Heating;
参考文献
Gardiner, John M.; Loyns, Colin R.; Schwalbe, Carl H.; Barrett, Garry C.; Lowe, Philip R.
Tetrahedron, 1995 , vol. 51, # 14 p. 4101 - 4110
反应条件
potassium carbonate in N,N-dimethyl-formamide T=110 - 120°C; 4 h;
参考文献
Orjales, Aurelio; Mosquera, Ramon; Labeaga, Luis; Rodes, Rosa
Journal of Medicinal Chemistry, 1997 , vol. 40, # 4 p. 586 - 593
参考文献
Squibb and Sons
Patent: US2407309 , 1942 ;
反应条件
1.1: sodium nitrite; sulfuric acid / water / 0 - 5 °C 1.2: 0 - 50 °C 2.1: lithium aluminium tetrahydride / benzene; diethyl ether / Cooling; Reflux; Inert atmosphere 2.2: pH 6 3.1: boric acid / 6 h / Reflux View Scheme
参考文献
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL; JIN, Jian; ROTH, Bryan; FRYE, Stephen
Patent: WO2012/3418 A2, 2012 ;
WO 2012/003418 A2
反应条件
sodium dithionite in methanol T=70°C; 0.6 h;
参考文献
Zhou, Binhua; Li, Baojian; Yi, Wei; Bu, Xianzhang; Ma, Lin
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 13 p. 3759 - 3763
参考文献
Siqueira, Fernanda A.; Taylor, Jason G.; Correia, Carlos Roque D.
Tetrahedron Letters, 2010 , vol. 51, # 16 p. 2102 - 2105
