7-(2-脱氧-beta-D-赤式-呋喃戊糖基)-1H-吡咯并[2,3-d]嘧啶-2,4(3H,7H)-二酮合成路线 （共 4 条）
反应条件
hydrogen bromide; acetic acid in tetrahydrofuran
Heating;
参考文献
Seela, Frank; Driller, Hansjuergen; Liman, Ulrich
Liebigs Annalen der Chemie, 1985 , p. 312 - 320
反应条件
1: 1.) 25percent HCl, NaNO2; 2.) CuCl / 1.) H2O, 5 deg C, 15 min 2.) 80 deg C, 15 min
2: 94 percent / methanol / 168 h / Heating
3: 67 percent / benzyltriethylammoniumchloride, 50percent NaOH / CH2Cl2 / 0.17 h
4: 60 percent / HBr/glacial acetic acid / tetrahydrofuran / Heating
View Scheme
参考文献
Seela, Frank; Driller, Hansjuergen; Liman, Ulrich
Liebigs Annalen der Chemie, 1985 , p. 312 - 320
反应条件
1: 67 percent / benzyltriethylammoniumchloride, 50percent NaOH / CH2Cl2 / 0.17 h
2: 60 percent / HBr/glacial acetic acid / tetrahydrofuran / Heating
View Scheme
参考文献
Seela, Frank; Driller, Hansjuergen; Liman, Ulrich
Liebigs Annalen der Chemie, 1985 , p. 312 - 320
反应条件
1: 94 percent / methanol / 168 h / Heating
2: 67 percent / benzyltriethylammoniumchloride, 50percent NaOH / CH2Cl2 / 0.17 h
3: 60 percent / HBr/glacial acetic acid / tetrahydrofuran / Heating
View Scheme
参考文献
Seela, Frank; Driller, Hansjuergen; Liman, Ulrich
Liebigs Annalen der Chemie, 1985 , p. 312 - 320
