反应条件
1: 98 percent / Et3N / toluene / 5 h / Ambient temperature 2: 1.) NaH, 2.) benzyl bromide / 1.) THF, toluene, -20 deg C, 1 h, 2.) THF, toluene, -20 deg C, 2 h 3: DBU / toluene; tetrahydrofuran / 2 h 4: 89 percent / phosphate buffer pH 3 / 2.5 h / Ambient temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 42, # 7 p. 1381 - 1387
