2-甲氧基-6-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)吡嗪合成路线 (共 1 条)
反应条件
water; potassium acetate; tris-(dibenzylideneacetone)dipalladium(0); tri-cyclo-hexyl-phosphine in ethylene glycol dimethyl ether
T=150°C; 3 h;
参考文献
ASTRAZENECA AB; ASTEX THERAPEUTICS LTD
Patent: WO2007/145571 A1, 2007 ;
Location in patent: Page/Page column 88 ;
WO 2007/145571 A1