3-氧代-3-(喹啉-2-基)丙酸乙酯合成路线 （共 4 条）
反应条件
potassium tert-butylate
T=20°C; Claisen condensation; 0.25 h;
参考文献
Largy, Eric; Hamon, Florian; Rosu, Frederic; Gabelica, Valerie; De Pauw, Edwin; Guedin, Aurore; Mergny, Jean-Louis; Teulade-Fichou, Marie-Paule
Chemistry - A European Journal, 2011 , vol. 17, # 47 p. 13274 - 13283
反应条件
sodium ethanolate; toluene
参考文献
Campbell et al.
Journal of the American Chemical Society, 1946 , vol. 68, p. 1844
反应条件
1: HCl / 15 h / Heating
2: 5.91 g / potassium tert-butoxide / 0.25 h / 20 °C
View Scheme
参考文献
Chan, Bryan K.; Ciufolini, Marco A.
Journal of Organic Chemistry, 2007 , vol. 72, # 22 p. 8489 - 8495
反应条件
hydrogenchloride in 1,4-dioxane; water
T=100°C; 16 h;
参考文献
Largy, Eric; Hamon, Florian; Rosu, Frederic; Gabelica, Valerie; De Pauw, Edwin; Guedin, Aurore; Mergny, Jean-Louis; Teulade-Fichou, Marie-Paule
Chemistry - A European Journal, 2011 , vol. 17, # 47 p. 13274 - 13283
