反应条件
1.1: N-ethyl-N,N-diisopropylamine / acetonitrile / 0.5 h / 20 °C 2.1: lithium hexamethyldisilazane / tetrahydrofuran; hexane / 0.03 h / -50 °C / Inert atmosphere 3.1: 18-crown-6 ether; potassium carbonate / toluene; acetonitrile / 1 h / 20 °C / Inert atmosphere 3.2: 5 h / -20 °C / Inert atmosphere 4.1: hydrogenchloride / methanol; water / 1 h / Reflux 4.2: 0.17 h / 20 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 59, # 7 p. 885 - 888
