反应条件
1: 1.) hexamethyldisilazane, trimethylchlorosilane, 2.) LiBH4 / 1.) reflux, 2h, 2.) ether, reflux, 4h
2: 1.) triphenylphosphine, 2.) carbon tetrachloride, pyridine / 1.) DMF, 10 min, 2.) DMF, RT, 1.5 h
View Scheme
参考文献
Griengl, Herfried; Bodenteich, Michael; Hayden, Walter; Wanek, Erich; Streicher, Wolfgang; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 11 p. 1679 - 1684
