1: 95 percent / Na2CO3 / H2O / Heating 2: 87 percent / thionyl chloride / Heating 3: 98 percent / sulfur / xylene / Heating; lead tetraacetate as reagent in pyridine; 4: 96 percent / aq.NaOH / ethanol / Heating 5: diphenylphosphoryl azide; triethylamine; acetic acid; NaOH; View Scheme

1: 95 percent / Na2CO3 / H2O / Heating 2: 87 percent / thionyl chloride / Heating 3: 98 percent / sulfur / xylene / Heating; lead tetraacetate as reagent in pyridine; 4: 96 percent / aq.NaOH / ethanol / Heating View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: ethanol / 1 h / 20 &deg;C<br />2: sodium / ethanol; 20 deg C; 3 days;<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 85 percent / NaH / tetrahydrofuran / 4 h / 25 &deg;C<br />2: 95 percent / aq. NaCl / dimethylsulfoxide / 3 h / 180 - 190 &deg;C<br />3: 66 percent / Raney nickel / ethanol / 6 h / Heating<br /> <br /> &nbsp;